Spectrophotometric determination of halogen-containing organic pharmaceuticals using 1,5-bis(6-methyl-4-pyrimidyl)carbazone. IV.
نویسندگان
چکیده
A spectrophotometric method for the determination of chlorine,bromine or iodine ion by using1,5-bis(6-methy1-4-pyrimidyl)carbazone has been established.The ranges of determination were0.355-3.55ppm of Cl-,0.799-7.99ppm of Br and1.27-12.7ppm of F.The proposed method could be applied to the analyses of various halogen-containing organic compounds, including sulfur-containing compounds.Eleven commercial pharmaceutical preparations gave precision(R.S.D.)values in the range of0.2%to5.6%(replicate analysis),when they were processed by the oxygen flask combustion method. Keywords-spectrophotometric determination;silver complex;oxygen flask combustion; halogen-containin .;compound;1,5-bis(6-methy1-4-pyrimidyl)carbazone;drug assay
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ورودعنوان ژورنال:
- Chemical & pharmaceutical bulletin
دوره 36 12 شماره
صفحات -
تاریخ انتشار 1988